Cypermethrin-Induced Lung Damage in Albino Rats: The Preventive Impact of Moringa oleifera

نویسندگان

چکیده

Cypermethrin (CYP) is a popular environmental toxicant because of its wide-ranging use as broad-band insecticide. The purpose this research was to explore the potential impact Moringa oleifera leaves extract (MOLE) protective agent against cypermethrin-induced lung toxicity in male albino rats. Forty experimental animals were allocated into four groups. G1 served negative control, G2, G3 and G4 orally treated with MOLE (250 mg/kg body weight), CYP (26.15mg/kg weight) + MOLE, respectively. oral administration for 28 days elevated levels oxidative stress biomarkers like Malondialdehyde, superoxide dismutase, catalase glutathione S-transferase caused decline content reduced tissue Lung injury verified by histopathological changes evidenced interstitial pneumonia, marked perivasculitis, focal pulmonary hemorrhage, haemosidrosis edema CYP-exposed Co-administration mitigated induced alterations. As result, can prevent due free radical scavenging antioxidant properties.

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ژورنال

عنوان ژورنال: Egyptian Journal of Chemistry

سال: 2021

ISSN: ['0449-2285', '2357-0245']

DOI: https://doi.org/10.21608/ejchem.2021.73925.3658